Paul Vo, the inventor and originator of the technology used in the Moog Guitar, has gone in his own direction developing circuitry that transforms guitars into instruments that are capable of true acoustic synthesis. This interface is called the Vo-96.
Basically, it's one of the first truly portable self-amplifying synthesizers. It's an amazingly inspiring innovation. I had one installed in an acoustic guitar and it's now my favorite guitar to play.
http://www.voinventions.com