Mac Update to 10.13.4 -> USB fails !?!?!

Hi Yesterday i updated my iMac to 10.13.4 , the latest patch. Before that my system was running well. Now i can’t use the USB links for the Editor etc anymore. It will not work. I’ve switched to MIDI instead. That is working.

This Mac Update made me crazy , spent hours of hours to figure it out. Anyone have the same issue ?

Best,
Tom