Seems with the update to 1.05 my Moog 16v got rather unstable tuning. It may have to do with my own made patches and/or leaving the Moog on for several hours. Will have to investigate more on that.
Making your own patches should not make it unstable! I had the same issue (16v). Especially after a while, it would get so out of tune I would have to reset the machine!
fwiw—My One 16v (running 1.05) has been powered up for about four hours today and seems to be staying in tune. Checked it a couple of times with a chromatic tuner.
Hi folks, mine has the same issue. Upgrading to 1.0.5 had no changing effect, today, after 4 hours my MO16 ran again into a detuned state. Had to power down and up. But not all sounds were affected by the detuned state, I think, it depends on the waveform is used by the sound. Hope for a solution by 1.0.6 for us.
Its a good day today, I will try out the brand new 1.06 update !
Interesting features und bug fixes are included. 
Agreed. 1.0.6 is a nice update. Been having fun testing it out.
Thanks Moog people for the update.
1.0.6 also features some real tuning improvements, so you may want to upgrade…